The PowerPlex 16 HS System is a multiplex STR system for use in DNA typing. This system co-amplifies the loci Penta E, D18S51, D21S11, TH01, D3S1358 (labeled with fluorescein); FGA, TPOX, D8S1179, vWA and Amelogenin (labeled with TMR); Penta D, CSF1PO, D16S539, D7S820, D13S317 and D5S818 (labeled with JOE). This multiplex includes all 13 CODIS STR markers, Amelogenin for gender determination and two low-stutter, highly discriminating pentanucleotide STR markers. All sixteen loci are amplified simultaneously in a single tube and analyzed in a single injection. The PowerPlex 16 HS System is compatible with ABI PRISM 310, 3100 and 3100-Avant Genetic Analyzers and Applied Biosystems 3130, 3130xl, 3500 and 3500xL Genetic Analyzers.|
Generate Profiles with Samples that Previously Failed to Amplify: The PowerPlex(R), 16 HS System is more tolerant of PCR inhibitors than competing STR systems and the previous version of the PowerPlex(R), 16 System. Avoid costly and time-consuming sample cleanup.
Gain Confidence in Analysis of Limited Samples: Each lot is quality tested to produce full profiles from 100pg of DNA.
Achieve High Discrimination: The loci included in the PowerPlex(R), 16 HS System are more discriminating than competitive systems and are ideal for resolving partial matches or challenging familial cases.
Expect Concordance with Existing Databases: Primer sequences, dyes and ladders are all unchanged from the PowerPlex(R), 16 System.
Use a Complete System: The PowerPlex(R), 16 HS System includes size standard, amplification-grade water and Taq DNA polymerase already in the master mix. Simple to order, easy to use.
Automatically Assign Genotypes: Panels and bins text files are required for automatic assignment of genotypes using the GeneMapper(R), ID and ID-X software and are available for download.