The p75 neurotrophin receptor (p75(NTR)), also known as low-affinity NGF receptor (LNGFR) and p75(LNGFR), binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. p75(NTR) plays an important role in neurotrophic factor signaling including neuronal apoptosis. Anti-Human p75 pAb provides a valuable tool for understanding the role of p75(NTR) in neuronal death.|
Immunogen: Cytoplasmic domain of the human p75 neurotrophin receptor.Antibody Form: Purified rabbit IgG; 1mg/ml in PBS containing 50microg/ml gentamicin.Specificity: Human, rat, mouse and chicken p75.